Assembling and analysing terabases of DNA sequence
I will talk about FM-index based approaches to the genome sequence
assembly problem, and/or using Ancestral Recombination Graphs (ARGs) to efficiently
discover genetic variation from population DNA sequence data.
Richard Durbin is a Senior Group Leader at The Wellcome Trust Sanger
Institute. He is currently co-leading the 1000 Genomes Project to
produce a deep catalogue of human genetic variation by large scale
sequencing using next generation technologies. Previously Richard
contributed to the human genome project, the C. elegans genome
sequencing project, and development of the Acedb genome database, the
Pfam and Treefam databases of protein families and the Ensembl genome
data resource. He has also made theoretical and algorithmic
contributions to biological sequence analysis.
Richard has a BA in Mathematics, and a PhD in Biology from Cambridge
University, where he was also a Research Fellow, at King's College, from
1986 to 1988. He was a Fulbright Visiting Scholar in Biophysics at
Harvard University from 1982 to 1983 and a Lucille P Markey visiting
Fellow in the Department of Psychology, Stanford University from 1988 to
1990. He was a staff scientist at the MRC Laboratory of Molecular
Biology from 1990 to 1996, and was Head of Informatics at the Sanger
Institute from 1992-2006 and Deputy Director from 1997 to 2006. He was
elected a Fellow of the Royal Society in 2004.
Richard's home page can be found at